Scientist, Stem Cell Biology Job at Flagship Pioneering, Inc.
Company Summary:
Flagship Labs 68 (FL68) is a highly dynamic, entrepreneurial, and innovation-driven organization seeking to hire an exceptional Scientist to join our team. FL68 is a privately held, well-funded, early-stage biotechnology company that is developing novel cell therapy platforms. FL68 leverages unique cell types and novel cell behaviors to perform entirely new therapeutic functions. Fully realized, the FL68 platform technology will be able to tackle a massive spectrum of diseases, drastically extending the reach of cell therapy for human health.
FL68 was founded by Flagship Pioneering, an innovation enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Since Flagship's founding in 2000, the firm has originated and fostered the development of nearly 100 scientific ventures resulting in $19+ billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents. These companies include Seres Therapeutics (MCRB), Moderna (MRNA), Syros Pharmaceuticals (SYRS), Rubius Therapeutics (RUBY), Axcella Health, Evelo Biosciences (EVLO), and Indigo Agriculture.
Position Summary:
FL68 is seeking an innovative and highly motivated Stem Cell Scientist with expertise in culturing and maintaining induced pluripotent stem cell (iPSCs) lines, directed cell differentiations, and cell engineering approaches. This candidate will play a vital role in the company's efforts to demonstrate platform capabilities and transition findings into early pre-clinical studies. This candidate must have a strong desire to work collaboratively within and across teams, have excellent communication skills, and be willing to work in a highly dynamic and fast-paced entrepreneurial environment.
Responsibilities:
- The successful candidate will work collaboratively as a project lead to design and execute experiments that support research activities, project goals, and platform development.
- Maintain sterile human/mouse stem cell and/or iPSC cell cultures and perform directed cell differentiations.
- Design and perform cell-based and molecular assays (e.g. ELISAs, Western Blots, qRT-PCR, metabolic) for in vitro
- Perform critical data analysis and troubleshoot experiments.
- Maintain an organized and up-to-date electronic lab notebook.
- Write and maintain high quality experimental protocols.
- Report experimental plans and results to scientific team and management.
- Strong ability to work collaboratively across the Flagship ecosystem.
Minimum Qualifications:
- PhD with relevant laboratory experience.
- Extensive experience with mammalian cell culture for iPSCs.
- Previous experience with performing and validating in vitro directed differentiations.
- Experience with molecular and cell biology assays.
- Team player and strong drive to learn and apply new skills.
- Excellent communication and presentation skills, capable of conveying technical information in a clear and thorough manner.
Preferred Qualifications:
- Experience with genetic manipulation of cells and flow cytometry.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, "FSP") do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
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