Research Associate II Job at BioIVT
Company Overview:
BioIVT, formerly BioreclamationIVT, is a leading global provider of high-quality biological specimens and value-added services. We specialize in control and disease state samples including human and animal tissues, cell products, blood, and other biofluids. Our unmatched portfolio of clinical specimens directly supports precision medicine research and the effort to improve patient outcomes by coupling comprehensive clinical data with donor samples.
Our Research Services team works collaboratively with clients to provide in vitro hepatic modeling solutions. And as the world’s premier supplier of ADME-Tox model systems, including hepatocytes and subcellular fractions, BioIVT enables scientists to better understand the pharmacokinetics and drug metabolism of newly discovered compounds and their effects on disease processes. By combining our technical expertise, exceptional customer service, and unparalleled access to biological specimens, BioIVT serves the research community as a trusted partner in ELEVATING SCIENCE®
BioIVT is a leader in transporter biology research, working with clients and partners to provide an array of best-in-class transporter research services and solutions, as well as hepatic disposition, drug interactions, and hepatotoxicity of pharmaceutical compounds and other chemicals. We are currently looking for a talented, detail-oriented, and scientist to fill an opening in our transporter assay service group. Experience in the ADME-Tox field as well as with RNA isolation and qRT-PCR using hepatocytes is desirable.
Position Overview:
The Research Associate will be responsible for performing cell-based in vitro transporter studies that will comply with regulatory (FDA, EMA) guidelines. This role will be responsible for conducting a wide array of complex cell-based assays, maintaining mammalian cell cultures, data analysis and summarization, and compound preparation.
The successful candidate will be a highly productive independent thinker who works well in a close-knit team. Excellent communication skills, both oral and written, as well as meticulous attention to detail are required. The ability to adapt to novel responsibilities is expected.
- Conducting in vitro cell-based transporter assays in 96-well plates using MDCK-II cells, as well as assays using membrane vesicles, and potentially hepatocytes. Manually, and automatically using robot equipment with dexterity
- Analysis of data generated using Excel and GraphPad Prism.
- Maintaining mammalian cell cultures using MDCK-II and potentially other cells.
- Ability to manage multiple projects simultaneously to meet internal and external deadlines.
- Meticulous attention to detail in following, correcting, and defining protocols,
- Perform experiments for clients that will comply with regulatory guidelines.
- Perform general lab responsibilities, logging of client compounds, compound preparation, creating buffers and solutions, performing serial dilutions, monitoring equipment, and maintaining inventories of lab supplies.
- Operate and maintain lab equipment with excellence including Automation.
- Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, following and modifying SOPs.
- Ideally, the candidate will demonstrate high proficiency across a wide range of in vitro ADME-Tox technologies and be capable of initiating new areas of investigation, as well as keeping current with emerging literature in the transporter, ADME, and DMPK fields.
- Working knowledge of drug transporter sciences and being capable of performing assays in cell lines or hepatocytes is desirable.
Attributes:
- Excellent written and verbal communication skills
- Ability to effectively present information to internal staff members
- Self-motivated
- Collaborative in a fast-paced team environment
- Able to cope with the pressure and meet the needs of a dynamic and rapidly growing company
Position Requirements
- Bachelor's in Biochemistry, Pharmacology, or related field and at least 2 years industry experience or equivalent combination of advanced degree and experience
- Related experience in the contract research or pharmaceutical industry
- Oral and written communication skills
- Meticulous attention to detail, able to troubleshoot
- Strong organizational skills, ability to manage numerous projects simultaneously
- Capable of organizing and presenting scientific data analysis, formulating conclusions, and executing experiments.
- Experience in a biotech/pharmaceutical and/or academic research setting, with strong experience in facilitating research program development and management of research resources is preferred
- Experience using purchasing software a plus (ERP, SAP, Oracle, Sage, Infor)
PHYSICAL DEMANDS:
- The role will require extended periods of computer work for data analysis and reporting
- Ability to work in a fast-paced environment and meet time and quality-based objectives
WORKING CONDITIONS:
- Able to occasionally work outside of normal business hours when required for client calls
We offer a comprehensive benefit package for eligible team members including medical, dental, vision, short-term/long-term disability, life insurance, hospital indemnity and accident insurance. We also offer a generous retirement plan with a company match. Eligible employees also enjoy competitive time-off policies. We are a collaborative environment that promotes growth from within. Enjoy company-sponsored events for the entire team!
We can’t wait to work with you!
We are an equal opportunity employer.
The Company is an AA/EEO/Veterans/Disabled Employer.
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