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Scientist I/Scientist II, Genomic Assessment Job at Tessera Therapeutics

Tessera Therapeutics Somerville, MA

Company Summary:

Tessera Therapeutics is pioneering Gene Writing™— a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy. Tessera Therapeutics was founded by Flagship Pioneering, a life sciences innovation enterprise that conceives, resources, and develops first-in-category companies to transform human health and sustainability.

Position Summary:

The Scientist I/II will be responsible for the molecular characterization of novel gene writers to advance candidate selection efforts. We are looking for a highly independent, enthusiastic, and self-motivated individual to work on developing tools to assess genomic consequences of gene writing. This individual will join a dynamic, collaborative and rapidly growing team.

Key Responsibilities:

  • Develop and lead new projects, experiments, scientific processes to support characterization of novel gene writers.
  • Establish a comprehensive suite of assays to interrogate genomic off-target events
  • Actively undertake technology development efforts in the gene editing space.
  • Keep up with advances in genomics and genome engineering and strategize on prioritizing and onboarding cutting-edge technologies to advance R&D efforts.

Preferred Qualifications:

  • Ph.D. in biological sciences. Title commensurate with experience.
  • Experience in hybrid capture and long range sequencing technologies (Pacbio, Oxford Nanopore)
  • Familiarity with ONE-Seq

More About Flagship Pioneering

Flagship Pioneering has conceived of and created companies such as Moderna Therapeutics (NASDAQ: MRNA), Editas Medicine (NASDAQ: EDIT), Omega Therapeutics (NASDAQ: OMGA), Seres Therapeutics (NASDAQ: MCRB), and Indigo Agriculture. Since its launch in 2000, Flagship has applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures. In 2021, Flagship Pioneering was ranked 12th globally on Fortune's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies.

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.


Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, "FSP") do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.




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